Holloway became the first fighter in UFC history to hold an undisputed interim title and a BMF title.
Holloway's knockout at the 4:59 mark of the fifth round was the latest stoppage in the UFC Championship fight.
Holloway's 22 wins in UFC competition rank him tied for fourth in UFC history behind Jim Miller (26), Andrei Arlovski (23) and Donald Cerrone (23).
Holloway has landed more than 100 significant strikes in 16 UFC fights, the most in the company's history. No other fighter has achieved such a performance more than 10 times.
Holloway has landed 3,378 significant strikes in UFC fights, the most in the company's history.
Holloway has landed a total of 3,622 strikes in UFC fights, the most in the company's history.
Holloway is the only fighter in UFC history to complete 29 Octagon appearances without a knockdown.
Holloway has absorbed 2,223 significant strikes in UFC matches, the most in company history.
All five of Gaethje's career losses have come by stoppage.
Gaethje appeared in 13 fights in the UFC and earned 13 fight night bonuses.
Gaethje's 13 UFC fight night bonuses since 2017 are the most of any fighter in the company.